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Acute Respiratory Distress Syndrome Overview

Acute Respiratory Distress Syndrome
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Category: Cardiorespiratory (Associated with Heart and Lungs)

Gene: ANLN

Variant Detected: Base Substitution C > G

Severity: Scale 3 has a moderate degree of severity, as it is not a fatal disease, though it can decrease the quality of life.

Mode of Inheritance: Autosomal Recessive

Test Overview: Acute respiratory distress syndrome (ARDS) is the leading cause of death in critical care medicine. The syndrome is typified by an exaggerated inflammatory response within the lungs. ARDS has been reported in many species, including dogs. It has been reported a fatal familial juvenile respiratory disease accompanied by occasional unilateral renal aplasia and hydrocephalus, in Dalmatian dogs.

Research Citation(s): PLoS Genet. 2017 Feb 21;13(2):e1006625. doi: 10.1371/journal.pgen.1006625. eCollection 2017 Feb.
J Comp Pathol. 2009 Nov;141(4):254-9. doi: 10.1016/j.jcpa.2009.05.008. Epub 2009 Jul 22.


Associated Breed(s): Dalmatian,  Mixed Breed,