BREEDERS DIRECT Order Swabs

dog

cat

products

O-Store

Canine Multiple System Degeneration (Chinese Crested) Overview

Canine Multiple System Degeneration (Chinese Crested)
US$ 94.00 RRP
US$ 85.00 REGISTERED USER PRICE
ADD TO CART

Category: Neurologic (Associated with the Brain, Spinal and Nerves)

Gene: SERAC1

Variant Detected: del GTAA and point mutation G>C

Severity: Scale 3 has a moderate degree of severity, as it is not a fatal disease, though it can decrease the quality of life.

Mode of Inheritance: Autosomal Recessive

Test Overview: Canine multiple system degeneration (Chinese crested type) and (kerry blue type) is a progressive inherited neurological disease affecting Chinese crested dogs. Affected dogs present at 3 to 6 months of age with tremors, abnormal gait and poor balance. Dogs gradually progress to severe gait abnormalities, balance issues, frequent falling, abnormal body posture, abnormal eye movement and eventually are unable to move.

Research Citation(s): Johnson GS, Mhlanga-Mutangadura T, Morava E, Kozicz T, Taylor JF, O’Brien DP, Schnabel RD. Canine Multiple System Degeneration is Associated with Distinct SERAC1 Mutations in Two Different Dog Breeds [abstract]. Presented at the 63rd Annual Meeting of the American Society of Human Genetics in Boston, Massachusetts; 2013 Oct 22-26.

Associated Breed(s): Chinese Crested,  Mixed Breed,