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Dry Nose (Hereditary Nasal Parakeratosis) Overview

Dry Nose (Hereditary Nasal Parakeratosis)
US$ 75.00 RRP
US$ 67.50 REGISTERED USER PRICE
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Category: Dermatologic (Associated with Skin)

Gene: SUV39H2 on Chromosome 2

Variant Detected: Base Substitution T>G

Severity: Scale 2 has a low degree of severity. It has mild effects and generally does not pose any significant health concerns, or is easily managed.

Mode of Inheritance: Autosomal Recessive

Test Overview: Also referred to as Hereditary Nasal Parakeratosis (HNPK). Affected dogs begin showing clinical signs around six to twelve months of age. They develop dry, rough crusts on the tip of the nose. In extreme cases, the dog’s nose will crack causing severe discomfort. Lesions can occur on the area around the nose. The noses of these affected dogs are prone to bacterial infections and can lose pigment over time. This disorder may be treated with veterinary consultation and topical therapy.

Research Citation(s):
PLoS Genet. 2013;9(10):e1003848. doi: 10.1371/journal.pgen.1003848. Epub 2013 Oct 3. [PubMed: 24098150]
Vet Dermatol. 2003 Apr;14(2):103-10. [PubMed: 12662268]


Associated Breed(s): Labradoodle ,  Labrador Retriever,  Mixed Breed,