Abbreviated as AMS this condition is somewhat rare and results in the dog slowly but progressively over-grooming (licking) or biting their pads and paws leading to bleeding and ulceration.

This leads to bacterial and fungal infections and in many cases ulcers.

Symptoms can be managed by using 'elizabeth' cones or anti-anxiety medication.

if the disorder cannot be managed then euthanasia is common.

It is neurological seen in a mutation of the GDNF gene affecting the development of the axon in the dog's neurons, this leads to a decrease in the sensation to recognise pain and temperature sensation.