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Canine Multifocal Retinopathy CMR3 Overview

Canine Multifocal Retinopathy CMR3
US$ 75.00 RRP
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Category: Ophthalmologic (Associated with the Eyes)

Gene: BEST1 Exon 10 Variant 2 on Chromosome 18

Variant Detected: Deletion of C

Severity: Scale 3 has a moderate degree of severity, as it is not a fatal disease, though it can decrease the quality of life.

Mode of Inheritance: Autosomal Recessive

Test Overview: Multifocal retinopathy 3 is an inherited disorder of the Retina affecting dogs. Affected dogs typically present between 9 months and 2 years of age with multiple discrete circular areas of retinal detachment with underlying fluid accumulation that are visible on an eye exam performed by a veterinarian. These blister-like lesions are typically found in both eyes and can appear gray, tan, orange or pink and vary in number, size and location. Some affected dogs also present with obvious retinal folding. Progression of retinal changes is usually slow. Occasionally as affected dogs age, lesions appear to heal and are no longer visible on an eye exam. Generally the dog’s vision is not affected although vision loss has been described in some cases of multifocal retinopathy 3.

Research Citation(s):
Mol Vis. 2010 Dec 16; 16:2791-804. [PubMed: 21197113]


Associated Breed(s): Lapponian Herder,  Finnish Lapphund,  Swedish Lapphund,