Gall Bladder Mucocele Formation (Shetland Sheepdog Type) Overview
Gall Bladder Mucocele Formation (Shetland Sheepdog Type)
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Category: Metabolic - Associated with the enzymes and metabolic processes of cells
Variant Detected: Insertion of G
Severity: Scale 4 has a high degree of severity. It generally causes a decreased quality of life and may also decrease the life expectancy.
Mode of Inheritance: Autosomal Recessive
Test Overview: ABCB4 functions as a phosphatidylcholine translocater, flipping phosphatidylcholine across hepatocyte canalicular membranes into biliary canaliculi.Hepatobiliary disease in dogs has been recognized with increased frequency during the past several years. In particular, gallbladder mucoceles (mucinous hyperplasia or mucinous cholecystitis) have been documented to be an increasingly important cause of hepatobiliary disease in dogs
Research Citation(s): Comp Hepatol. 2010; 9: 6.
Vet Radiol Ultrasound. 2000;41:261–271. doi: 10.1111/j.1740-8261.2000.tb01489.x
Associated Breed(s): Mixed Breed, Shetland Sheepdog,