O-Store

Spongy Degeneration with Cerebellar Ataxia (KCNJ10) Overview

Spongy Degeneration with Cerebellar Ataxia (KCNJ10)
US$ 75.00 RRP
US$ 67.50 REGISTERED USER PRICE
ADD TO CART

Category: Neurologic (Associated with the Brain, Spinal and Nerves)

Gene: Potassium voltage-gated channel subfamily J member 10 (KCNJ10) on Chromosome 38

Variant Detected: Base Substitution c.986T>C p.Leu329Pro

Severity: Scale 4 has a high degree of severity. It generally causes a decreased quality of life and may also decrease the life expectancy.

Mode of Inheritance: Autosomal Recessive

Research Citation(s): Mauri, N. et al. A Missense Variant in KCNJ10 in Belgian Shepherd Dogs Affected by Spongy Degeneration with Cerebellar Ataxia (SDCA1). (2017) G3 7(2);663-669.

Associated Breed(s): Belgian Groenendael Shepherd,  Belgian Lakenois Shepherd,  Belgian Malinois Shepherd,  Belgian Tervueren Shepherd ,  Mixed Breed,