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Body Size IGSF1 "Bulky Gene" (All Breeds) - SINGLE ASSAY TEST

US$ 75.00 RRP

US$ 40.00 (USER PRICE)

Test Overview:

The insulin-like growth factor-1 gene (IGF1), and additional studies of Miniature Poodles and Dachshunds implicated the IGF1 receptor (IGF1R) as well, both of which are important regulators of body size. The IGF1 pathway has also been established as important in normal stature in humans, and mutations in IGF1 have been shown to reduce body size in mice.

Category:

Trait (Associated with Phenotype)

Gene:

IGSF1

Variant Detected:

chrX.g.102369488-102369489insAAC, p.Asp376_Glu377insAsn, Chromosome X

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Plassais, 2017, PLoS Genet 13(3): e1006661

Associated Breed(s):

American Bulldog , American Bully , American Pit Bull Terrier, American Staffordshire Terrier, Australasian Bosdog, Australian Bulldog, Boerboel, Boxer , British Bulldog, Bull Arab, Bull Terrier, Bullmastiff, French Bulldog, Greyhound , Italian Greyhound, Mastiff , Miniature Australian Bulldog, Miniature Bull Terrier, Presa de Canario, Short Bully, Shortybull, Staffordshire Bull Terrier , Tibetan Mastiff, Whippet ,