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Hypocatalasia is a rare genetic disorder.
Symptoms have been poorly described or are missing from the literature.
It is suspected that affected dogs have a higher risk of developing open sores (ulcers) inside the mouth that may lead to gangrene of the mouth.
Affected dogs most commonly show no or few signs, and the disorder is usually diagnosed when checking other symptoms.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.
Gene:
CAT on Chromosome 18
Variant Detected:
Base Substitution G>A
Mode of Inheritance:
Recomended Screening:
Carriers can be bred to normal animals (N/hyp x N/N). Offspring should be tested before breeding. No breeding of two carriers (N/hyp x N/hyp) nor of affected animals (hyp/hyp). Affected animals may have progressive gangrene of the mouth
Research Citation(s):