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DSRA (Dental-Skeletal-Retinal Anomaly) is a genetic condition in the Cane Corso breed, causing abnormal development of bones and teeth, which may become brittle, discolored, or translucent.
The condition progresses to retinal degeneration, leading to vision loss.
This disorder is linked to a mutation in the MIA3 gene, responsible for producing a protein crucial for exporting collagen and other proteins.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.
Gene:
MIA3
Variant Detected:
deletion chr38
Mode of Inheritance:
Recomended Screening:
Research Citation(s):