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The Harlequin gene causes a white background and the spots increase in size.
Dogs that are not merle, cannot express the Harlequin colour/pattern.
Breeding two dogs that both have a copy of the h locus “NH” is not recommended.
A dog with two copies of Harlequin has not been observed and It is presumed to be lethal in utero.
This gene is inherited as a dominant trait.
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Associated Breed(s):
Click here to view Associated Breeds
Category:
Genetic Traits
Severity:
Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.
Gene:
PSMB7
Variant Detected:
Base Substitution T>C
Mode of Inheritance:
Recomended Screening:
Research Citation(s):