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Breeds Affected: Maine Coon, Abbysinian, Bengal, Egyptian Mau, Norwegian Forest CatOne of the most common causes of cardiac disease in cats.
The MYBPC3 gene is seen as the candidate (causative) gene leading to the reduction in the myocardium protein.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.
Gene:
MYBPC
Variant Detected:
Base Substitution G>C
Mode of Inheritance:
Recomended Screening:
1. Recommend genetic screening of all breeding animals (if available) at or before 1 year of age 2. Echocardiography at 1 year of age and recommend yearly for breeding animals for 3-4 years of age, then repeat every 2-3 years 3. Careful auscultation of all animals annually and echocardiogram of any animals with abnormal auscultation findings
Research Citation(s):