It is a form of group of neurodegenarative disorders, the neuronal ceroid lipofuscinoses (NCLs).

They are known to affect humans, cats, sheep, goats, monkey, cattle etc.

The neuronal ceroid lipofuscinoses (NCLs) are divided into genetically distinct forms, all causing accumulation of lipopigments in the body’s tissue.

To date NCLs have been associated with 8 different genetic mutations.

Another classification of NCLs includes age of onset, so they are divided into infantile (INCL), late-infantile, juvenile and adult onset forms.

NCL 10 American Bulldog Type differs from other forms of NCLs, due to its impact on locomotion and no affect on the vision of the dog.