Cardiomyopathy and Juvenile Mortality (Belgian Shepherd) - SINGLE ASSAY TEST

$75.00 (RRP)



Cardiomyopathy and Juvenile mortality (CJM) is a poorly defined systemic disease.

Affected puppies die at birth or at a maximum age of 6-8 weeks. In a recently reported case, the puppies initially developed normally but then showed non-specific symptoms like vomiting, uncoordinated movements, trembling or respiratory symptoms and died a few days after the first clinical signs, usually due to heart failure.


Cardiorespiratory (Associated with Heart and Lungs)


YARS2, chr13

Variant Detected:

c.1054G>A p.Glu352Lys


Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Dominant

Research Citation(s):

Gurtner, 2020, Genes, 11,313

Associated Breed(s):

Belgian Groenendael Shepherd, Belgian Lakenois Shepherd, Belgian Malinois Shepherd, Belgian Tervueren Shepherd ,