Progressive Retinal Atrophy - crd1PRA Overview
Progressive Retinal Atrophy - crd1PRA
US$ 75.00 RRP
US$ 67.50 REGISTERED USER PRICEADD TO CART
Category: Ophthalmologic - Associated with the eyes and associated structures
Gene: Beta subunit of the cGMP phosphodiesterase gene (PDE6B) on chromosome 3
Variant Detected: Nucleotide Deletion c.2404-2406del p.Asn802del
Severity: Scale 1 has a very low degree of severity. It is a trait and so is tested based on preference, not usually for health concerns.
Mode of Inheritance: Autosomal Recessive
Research Citation(s): Goldstein O, et al. IQCB1 and PDE6B mutations cause similar early onset retinal degenerations in two closely related terrier dog breeds. (2013) Invest Ophthalmol Vis Sci 54(10);7005-7019.
Associated Breed(s): American Staffordshire Terrier, American Pit Bull Terrier,