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Progressive Retinal Atrophy (Shetland Sheepdog) Overview

Progressive Retinal Atrophy (Shetland Sheepdog)
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Category: Ophthalmologic - Associated with the eyes and associated structures

Gene: CNGA1

Variant Detected: c.1752_1755delAACT

Severity: Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Mode of Inheritance: Autosomal Recessive

Test Overview: PRA is characterized by visual impairment due to degeneration of the photoreceptors in the retina, usually leading to blindness. The disease can be subdivided by age at onset and rate of progression.

Research Citation(s): Anim Genet. 2015 Jul 22. doi: 10.1111

Associated Breed(s): Shetland Sheepdog,  Mixed Breed,