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This is an inherited disorder neuro-degenerative disorders characterized by progressive degeneration of cerebellum and extracerebellar structures, these brain structure help coordinate movement.
Affected puppies start to show symptoms around 4 weeks of age. Symptoms include generalized abnormal gait, seizures, and pacing as well as circling and central blindness. These clinical signs showed very rapid progression. Affected puppies may die during a seizure.
Nervous system / Neurologic - Associated with the brain, spinal cord and nerves
It is a trait and so is tested based on preference, not usually for health concerns.
Mode of Inheritance:
Mauri, N., Kleiter, M., Dietschi, E., Leschnik, M., Högler, S., Wiedmer, M., … Leeb, T. (2017). A SINE Insertion in ATP1B2 in Belgian Shepherd Dogs Affected by Spongy Degeneration with Cerebellar Ataxia (SDCA2). G3: Genes|Genomes|Genetics, 7(8), 2729–2737. http://doi.org/10.1534/g3.117.043018
Associated Breed(s):Belgian Groenendael Shepherd, Belgian Lakenois Shepherd, Belgian Malinois Shepherd, Belgian Tervueren Shepherd , Mixed Breed,