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The protein melanophilin (MLPH gene) is responsible for the dilute coat colour. This variation causes black, brown and yellow hair (eumelanin or phaeomelanin pigments) to be diluted. Referred to as blue, charcoal, grey and in cobination with other colours lilac or champagne. A normal result is usually reported as DD (no copies of dilute), with carrier as Dd (one copy of the dilute) and a dilute colour dog affected is reported dd.
The protein melanophilin (MLPH gene) is responsible for the dilute coat colour. This variation causes black, brown and yellow hair (eumelanin or phaeomelanin pigments) to be diluted. Referred to as blue, charcoal, grey and in combination with other colours - lilac or champagne. A normal result is usually reported as DD (no copies of dilute), with carrier as Dd (one copy of the dilute) and a dilute colour dog affected is reported dd.
Trait (Associated with Phenotype)
It is a trait and so is tested based on preference, not usually for health concerns.
Mode of Inheritance:
University of Bern, 02 May 2007. Web. 02 Apr. 2014.
Sir James Dunn Animal Welfare Centre and the Canadian Veterinary Medical Association, 02 Feb. 2004. Web. 03 Apr. 2014.
. J Hered. 2007; 98(5):468-73. [PubMed: 17519392]
. Vet Rec. 1995 Oct 14;137(16):412. [PubMed: 8545945]
Vet Rec. 1988 Apr 9;122(15):360-1.
Aust Vet J. 1993 Oct;70(10):388-9. [PubMed: 8257319] Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs.
BMC Genet. 2005 Jun 16; 6:34. [PubMed: 15960853]
Associated Breed(s):Affenpinscher, Afghan Hound, Airedale Terrier, Akita , Alaskan Husky, Alaskan Malamute, American Bulldog , American Bully , American Cocker Spaniel, American Eskimo Dog, American Foxhound, American Hairless (Rat) Terrier, American Pit Bull Terrier, American Staffordshire Terrier, Anatolian Shepherd, Asian Shepherd, Australasian Bosdog, Australian Bulldog, Australian Cattle Dog, Australian Cobberdog, Australian Kelpie, Australian Labradoodle , Australian Shepherd, Australian Silky Terrier, Australian Stumpy Tail Cattle Dog, Australian Terrier, Basenji, Basset Hound, Beagle, Bearded Collie , Bedlington Terrier, Belgian Groenendael Shepherd, Belgian Lakenois Shepherd, Belgian Malinois Shepherd, Belgian Tervueren Shepherd , Bernese Mountain Dog, Bichon Frise, Black Russian Terrier , Bloodhound, Boerboel, Border Collie, Border Terrier, Borzoi, Boston Terrier, Bouvier Des Flandres, Boxer , Boykin Spaniel, Bracco Italiano, Brazilian Terrier, Briard, British Bulldog, Brittany Spaniel , Bull Arab, Bull Terrier, Bullmastiff, Cairn Terrier, Canaan Dog, Cane Corso Italiano, Cardigan Welsh Corgi, Catahoula, Catahoula Leopard Dog, Cavador, Cavalier King Charles Spaniel, Cavoodle, Chesapeake Bay Retriever , Chihuahua, Chinese Crested, Chow Chow, Clumber Spaniel , Cockapoo, Cocker Spaniel, Collie Rough, Collie Smooth, Coonhound, Coton De Tulear, Curly Coated Retriever, Dachshund , Dalmatian, Dandie Dinmont Terrier, Dingo, Dobermann, Dogue de Bordeaux, Double Doodle, Dutch Shepherd, Dwarf Poodle, English Pointer, English Setter , English Shepherd, English Springer Spaniel, English Toy Spaniel , English Toy Terrier, Field Spaniel, Finnish Lapphund, Flat Coated Retriever, Fox Terrier (Toy), Foxhound , French Bulldog, German Pinscher, German Shepherd Dog, German Shorthaired Pointer, German Spitz , German Wirehaired Pointer, Giant Schnauzer, Glen of Imaal Terrier, Golden Retriever, Goldendoodle, Gordon Setter , Grand Basset Griffon Vendeen, Great Dane, Great Pyrenees, Greater Swiss Mountain Dog, Greyhound , Griffon Bruxellois - Standard, Groodle, Harlequin Pinscher, Havanese, Havanese Terrier Toy, Hungarian Kuvasz, Hungarian Vizsla, Huntaway, Ibizan Hound, Irish Setter, Irish Terrier, Irish Water Spaniel, Irish Wolfhound, Italian Greyhound, Italian Spinone, Jack Russell Terrier, Jagd Terrier, Japanese Chin, Japanese Shiba Inu, Japanese Spitz, Kaninchen Dachshund, Keeshond, Kerry Blue Terrier, Komondor, Koolie , Kromfohrländer, Labradoodle , Labradoodle Retrodoodle , Labrador Retriever, Lagotto Romagnolo, Lakeland Terrier , Lancashire Heeler, Landseer ECT, Lapponian Herder, Large Munsterlander, Leonberger, Lhasa Apso, Lowchen, Maltese, Manchester Terrier , Maremma Sheepdog, Mastiff , Miki, Miniature American Shepherd, Miniature Australian Bulldog, Miniature Bull Terrier, Miniature Dachshund, Miniature Dachshund Long Hair, Miniature Dachshund Smooth Hair, Miniature Dachshund Wire Hair, Miniature Fox Terrier, Miniature Pinscher , Miniature Poodle, Miniature Schnauzer, Miniature Yorkshire Terrier, Mixed Breed, Moodle, Mountain Dog , Moyen Poodle, Munsterlander, Murray River Retriever, Native American Indian Dog, Neapolitan Mastiff, New Zealand Heading Dog, Newfoundland, Norfolk Terrier , Norwegian Elkhound, Norwich Terrier, Nova Scotia Duck Tolling Retriever , Old Danish Pointing Dog, Old English Mastiff , Old English Sheepdog , Otterhound, Papillon, Parson Russell Terrier, Pekingese, Pembroke Welsh Corgi, Peruvian Hairless Dog, Petit Basset Griffon Vendeen, Phalene, Pharaoh Hound, Plott Hound, Pointer, Polish Lowland Sheepdog, Pomeranian, Portuguese Podengo, Portuguese Water Dog, Prague Ratter, Presa de Canario, Pug, Puli, Pumi, Rat Terrier, Red and White Setter, Rhodesian Ridgeback , Rottweiler , Russian Toy, Saint Bernard , Saluki, Samoyed, Sarplaninac, Schapendoes, Schipperke, Schnoodle, Scottish Deerhound, Scottish Terrier , Sealydale Terrier, Sealyham Terrier , Shar Pei, Shetland Sheepdog, Shiba Inu, Shih tzu, Short Bully, Shortybull, Siberian Husky, Silky Terrier , Skye Terrier, Sloughi, Smithfield, Smooth Fox Terrier, Soft Coated Wheaten Terrier, Spanatriever, Spanish Water Dog, Spoodle, Staffordshire Bull Terrier , Standard Dachshund Long Hair, Standard Dachshund Smooth Hair, Standard Dachshund Wire Hair, Standard Poodle, Standard Schnauzer, Sussex Spaniel, Swedish Lapphund, Swedish Vallhund, Tenterfield Terrier , Tibetan Mastiff, Tibetan Spaniel, Tibetan Terrier , Toy Poodle, Volpino Italiano, Water Spaniel , Weimaraner, Weimaraner Long Hair , Welsh Springer Spaniel, Welsh Terrier , West Highland White Terrier , Whippet , White Swiss Shepherd, Wire Fox Terrier, Wirehaired Vizsla, Xoloitzcuintle (Mexican Hairless), Yorkshire Terrier,