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D2 (Dilute) Locus Overview

D2 (Dilute) Locus
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Category: Trait (Associated with Phenotype)

Gene: MLPH

Variant Detected: c.705G>C

Severity: It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance: Autosomal Recessive

Test Overview: A new mutation causing dilution of coat colour in many other breeds such as Chow-Chow,Arabian Greyhound and Thai Ridgeback.

Research Citation(s): Bauer A. et al (2018): A novel MLPH variant in dogs with coat colour dilution. Anim Genet. 49(1):94-97. doi: 10.1111/age.12632. Epub 2018 Jan 19

Associated Breed(s): Mixed Breed,  Chow Chow,  Sloughi,