E Locus e2 Overview
E Locus e2
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Category: Trait (Associated with Phenotype)
Severity: Scale 1 has a very low degree of severity. It is a trait and so is tested based on preference, not usually for health concerns.
Mode of Inheritance: Autosomal Recessive
Test Overview: The pale cream colour produced by the e2 variant occurs in Australian Cattle Dog and appears limited to this breed and its crossbreds
Research Citation(s): Durig N, A Letko, SH Rasouliha, R Loechel, A Kehl, MK Hytonen, H Lohi, N Mauri, J Dietrich, M Wiedmer, M Drogemuller, V Jagannathan, SM Schmutz, T Leeb. 2018. Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies. Animal Genetics 49:284-290.
Associated Breed(s): Mixed Breed, Australian Cattle Dog, Australian Shepherd,