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Orivet, a leader in innovative animal health, provides over 260 Tests for Dog Breeders including Single Assays - health and phenotype.
Degenerative Myelopathy (DM) is seen in over 60 breeds, it can be a debilitating disease that leads to the gradual paralysis in many breeds.
Typically seen at the age of around 8 to 14 years it presents with a loss of coordination in the hind legs.
The genetic test allows you to screen for this disease at an early age.
Please see more in Test Overview below.
$ 50.00
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Associated Breed(s):
Click here to view Associated Breeds
Category:
Genetic Diseases
Severity:
Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.
Gene:
Superoxide dismutase 1 (SOD1) on chromosome 31
Variant Detected:
Base Substitution c.118G>A p.Glu40Lys
Mode of Inheritance:
Recomended Screening:
1. All breeding animals should have a DNA test prior to entering into a breeding program - eg at 1 year of age. 2. Neurologic examination of all animals at annual veterinary check-up from middle age (3-4 years) onwards. 3. Offer DNA testing to all owners of puppies if his parents have not been screened.
Research Citation(s):