Vitamin D Rickets Overview
Vitamin D Rickets
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Category: Metabolic (Associated with the Body's Enzymes and Cell Metabolism)
Variant Detected: Deletion of a G; Base Substitution G>A
Severity: Scale 4 has a high degree of severity. It generally causes a decreased quality of life and may also decrease the life expectancy.
Mode of Inheritance: Autosomal Recessive
Test Overview: Clinical signs had been seen from four months of age. Treatment with calcium supplementation and various forms of vitamin D did not alter plasma calcium levels or reverse skeletal lesions of lateral antebrachial bowing, lumbar spinal lordosis and costochondral beading. Analgesics were effective for relieving skeletal pain during the bone growth phase and were withdrawn when the animal reached skeletal maturity. Therapy for hip osteoarthritis was given from five years of age until the cat was euthanased at nine years of age as a result of refractory hip pain.
Research Citation(s): J Vet Intern Med. 2009 Jan-Feb;23(1):196-
Associated Breed(s): Domestic Short Hair, Domestic Medium / Long Hair,