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Macroscopically, all dogs showed generalized gray to yellow scaling and skin wrinkles on the head and all 4 extremities.
Skin sections were histologically examined using hematoxylin and eosin, Heidenhain's Azan, and Sudan red III staining methods and by conducting the alcian blue/periodic acid Schiff (AB/PAS) reaction technique on sections.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Low. This disease generally causes mild signs of disease, or can be quite easily treated/managed.
Gene:
Solute carrier family 27 member 4 (SLC27A4) Chromosome 9
Variant Detected:
Base Substitution c.1268G>A p.Arg417Gln
Mode of Inheritance:
Recomended Screening:
Research Citation(s):