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Affected dogs typically present between 11 and 16 weeks of age with multiple discrete circular areas of retinal detachment with underlying fluid accumulation that are visible on an eye exam performed by a veterinarian.
These blister-like lesions are typically found in both eyes and can appear gray, tan, orange or pink and vary in number, size and location.
Progression of retinal changes is usually slow and new lesions are not noted after 6 to 12 months of age.
Occasionally as affected dogs age, lesions appear to heal and are no longer visible on an eye exam.
Generally the dog’s vision is not affected although vision loss has been described in some cases of multifocal retinopathy 1.
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1
Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.
Gene:
Bestrophin 1 (BEST1) on chromosome 18
Variant Detected:
Base Substitution c.73C>T p.Arg25STOP
Mode of Inheritance:
Recomended Screening:
Research Citation(s):