Select your country
Loading...
Neonatal Encephalopathyis an inherited neurologic disease.
Affected puppies are smaller than littermates at birth, have difficulty nursing after a few days of life, and often die by 1 week of age.
By 3 weeks of age, surviving puppies present with neurologic symptoms including muscle weakness, tremors, inability to walk, wide-based stance and frequent falling.
The disease quickly progresses to severe seizures that become non-responsive to treatment.
Affected dogs typically die or are euthanized by 7 weeks of age.
$ 50.00
1
Associated Breed(s):
Click here to view Associated Breeds
Category:
Genetic Diseases
Severity:
Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.
Gene:
Activating transcription factor 2 (ATF2) on Chromosome 36
Variant Detected:
Base Substitution c.152T>G p.Met51Arg
Mode of Inheritance:
Recomended Screening:
Research Citation(s):