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Canine dental hypomineralization or Raine Syndrom is a genetic disorder affecting the Border Collies.
The disorder causes severe tooth wear resulting in pulpitis and requiring extraction of those teeth.
Dental hypomineralization is a canine model for human Raine Syndrome.
Dental examination of the affected dogs reveals a significant wear.
Lower incisor teeth can be worn close to the gingival margin.
The enamel shows a light brown discoloration and appears dull.
Some worn teeth can have a pulp exposure and pulpits as a result of the wear.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.
Gene:
FAM20C
Variant Detected:
c.899C>T
Mode of Inheritance:
Recomended Screening:
Research Citation(s):