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Sensory neuropathy Border Collie type is an inherited progressive neurological disorder which affects the Border Collie breed.
Generally, neuropathy is a disease of the peripheral nerves.
The peripheral nervous system is responsible for sensation feeling to the skin and the muscle control.
Disease of the sensory nerves causes the sensory neuropathy.
Sensory neuropathy can be divided into two groups, inherited or acquired through disease processes or trauma.
Inherited sensory neuropathy is a rare disorder but has been reported in several countries worldwide.
Affected dogs start to show symptoms between the ages of 5 and 7 months.
Clinical signs include loss of coordination, joint laxity, lack of awareness where the limbs are in space, and inability to perceive pain.
Affected dogs often have self-mutilated limbs, which may be due to tingling or pain in their paws, another manifestation of the disorder.
Since the disorder is progressive and the symptoms are severe, affected dogs are usually euthanized.
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Associated Breed(s):
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Category:
Genetic Diseases
Severity:
Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.
Gene:
FAM134B
Variant Detected:
Inversion
Mode of Inheritance:
Recomended Screening:
Research Citation(s):